Start up Renoise. Click on Help -> Show the Preferences Folder. Open up Config.XML. Zoom down to 
<!--Gui-->
and add the code at the bottom of this page to it.
What will this do? Well:
F2 becomes the Pattern Editor, with Cursor-Focus on the Pattern Editor
F3 becomes the Sample Editor + Disk Browser + Instrument Settings, with Cursor-Focus on the Disk Browser
F10 becomes the Mixer + Disk Browser + Instrument Settings, with Cursor-Focus on the Mixer
F11 becomes the Pattern Matrix + Large Mixer (=top & bottom are disabled), with Cursor-Focus on Pattern Matrix
Shift-F1 becomes Sample Editor + Disk Browser + Instrument Settings, with Cursor-Focus on the Sample-Editor
Shift-F3 becomes Large Sample-Editor with Instrument Settings.

P.S. These shortcuts will not work unless if your Preferences->Keys looks like this:

Please e-mail me at esaruoho@gmail.com if you have any improvement suggestions.

  <GlobalViewPresets>
    <GlobalViewPreset>
      <UpperFrameIsVisible>false</UpperFrameIsVisible>
      <LowerFrameIsVisible>false</LowerFrameIsVisible>
      <ActiveUpperFrameView>Track Scopes</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Pattern Editor</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Pattern Editor</FocusedView>
      <DiskBrowserCategory>Song</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>false</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>true</LowerFrameIsVisible>
      <ActiveUpperFrameView>Track Scopes</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Pattern Editor</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Pattern Editor</FocusedView>
      <DiskBrowserCategory>Song</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>false</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>true</LowerFrameIsVisible>
      <ActiveUpperFrameView>Track Scopes</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Sample Editor</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Instrument Settings</ActiveLowerFrameView>
      <FocusedView>Sample Editor</FocusedView>
      <DiskBrowserCategory>Sample</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>false</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>true</LowerFrameIsVisible>
      <ActiveUpperFrameView>Disk Browser</ActiveUpperFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Disk Browser</FocusedView>
      <DiskBrowserCategory>Sample</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>true</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>false</LowerFrameIsVisible>
      <ActiveUpperFrameView>Master Spectrum</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Pattern Editor</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Sample Editor</FocusedView>
      <DiskBrowserCategory>Song</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>true</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>true</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>true</LowerFrameIsVisible>
      <ActiveUpperFrameView>Disk Browser</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Mixer</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Instrument Settings</ActiveLowerFrameView>
      <FocusedView>Mixer</FocusedView>
      <DiskBrowserCategory>Sample</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>false</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>true</UpperFrameIsVisible>
      <LowerFrameIsVisible>true</LowerFrameIsVisible>
      <ActiveUpperFrameView>Disk Browser</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Pattern Editor</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Disk Browser</FocusedView>
      <DiskBrowserCategory>Sample</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>false</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>true</DiskBrowserIsExpanded>
    </GlobalViewPreset>
    <GlobalViewPreset>
      <UpperFrameIsVisible>false</UpperFrameIsVisible>
      <LowerFrameIsVisible>false</LowerFrameIsVisible>
      <ActiveUpperFrameView>Track Scopes</ActiveUpperFrameView>
      <ActiveMiddleFrameView>Mixer</ActiveMiddleFrameView>
      <ActiveLowerFrameView>Track DSPs</ActiveLowerFrameView>
      <FocusedView>Pattern Matrix</FocusedView>
      <DiskBrowserCategory>Song</DiskBrowserCategory>
      <AdvancedEditIsVisible>false</AdvancedEditIsVisible>
      <PatternMatrixIsVisible>true</PatternMatrixIsVisible>
      <DiskBrowserIsExpanded>false</DiskBrowserIsExpanded>
    </GlobalViewPreset>
  </GlobalViewPresets>